All times are eastern, so adjust accordingly.
| Second Round — Monday, March 22 | |||
| (2) Iowa vs. (7) Oregon | 12:10 p.m. | CBS | Bankers Life Fieldhouse |
| (1) Gonzaga vs. (8) Oklahoma | 2:40 p.m. | CBS | Hinkle Fieldhouse |
| (11) UCLA vs. (14) Abilene Christian | 5:15 p.m. | TBS | Bankers Life Fieldhouse |
| (5) Creighton vs. (13) Ohio | 6:10 p.m. | TNT | Hinkle Fieldhouse |
| (1) Michigan vs. (8) LSU | 7:10 p.m. | CBS | Lucas Oil Stadium Unity (South) |
| (4) Florida State vs. (5) Colorado | 7:45 p.m. | TBS | Indiana Farmers Coliseum |
| (2) Alabama vs. (10) Maryland | 8:45 p.m. | TNT | Bankers Life Fieldhouse |
| (3) Kansas vs. (6) USC | 9:40 p.m. | CBS | Hinkle Fieldhouse |